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A southbound vehicle crossed into the northbound lanes to pass a slower car and collided head-on with the Missouri vehicle.

If you know of a small, local business you want to see on "Rene on the Block," let us know!

Scott Air Force Base cancels next month's open house due to budget concerns and mission prioritization.

Police said the 16-year-old boy was located safe.

Patricia Racette will become artistic director of Opera Theatre of Saint Louis, succeeding James Robinson and enhancing her longtime relationship with the company.

Marshaun Futrell Jr. was rushed to an area hospital, where he was pronounced dead.

The Missouri Department of Health and Senior Services said a person who lives outside of St. Louis visited the St. Louis Aquarium from 1-6 p.m. on April 30.

The Yn's recount their harrowing escape from post-war Vietnam, surviving pirate attacks and a dangerous sea journey before resettling in the U.S. in 1979.

Police said the teen was taken to the hospital, where he was listed in "stable condition" as of Tuesday.

Adan Manzano was found dead in a Louisiana hotel while covering Super Bowl LIX.

Court documents say the man told police he took the vehicle "to do the Lord's work" and crashed it because there was "a demon in it."

The Democratic candidate positions herself as a statewide advocate while avoiding policy specifics in early campaign days.

The hour-long, 5 On Your Side special “The Fall of Saigon: 50 years later” debuts on our streaming app 5+ on Tuesday, May 6.

Edwardsville Community Unit School District #7 implemented a cellphone ban, where students can't use their phones in the classroom.

Lawmakers have until Friday to finish work on state spending for the coming year.

The Illinois secretary of state warned against an unnecessary rush for a REAL ID as Wednesday's federal government deadline approaches.

The Jefferson County Sheriff's Office said there was no immediate indication of foul play and that detectives were continuing to investigate.

In a statement, the fire department identified him as Corey McBride and said he had been with the department for nearly two decades.

A former animal control officer at St. Louis County Animal Care and Control offers an inside look at what might have helped prevent a parvovirus outbreak.

"It was terrifying but everyone really banded together to get the people who could get off the bus and take care of those who needed more help," the passenger said.