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The Clayton-based health giant is likely to face increased challenges as federal government tightens Medicaid eligibility and trims subsidies for Obamacare plans.

U.S. Immigration and Customs Enforcement agents detained the Mexican immigrant outside his home in suburban Lyons without a federal warrant. Now, nearly six months later, he is still detained.

The state audit would have examined the personnel department, whose director, Sonya Jenkins-Gray, was later fired. Gov. Mike Kehoe has since appointed her to the city's new police board.

The crash was about 11:50 p.m. Sunday on Illinois Route 3 near Ruby Street in Cahokia Heights. Two vehicles were involved.

Austen Mary Fields has a cancer that strikes fewer than 1 in 3 million people. Her family has gone to clinics in Mexico for help. They're waiting for results.

Patients fear the clinic’s closure will end their access to the latest research, clinical trials for new treatments, and specialists with expertise in treating Long COVID symptoms.

Columnist Bill McClellan writes: Aren’t you being a touch greedy, old people?

Too many people who qualify for food stamps in Missouri can't get them. The problem could get worse soon.

Drink makers say they're targeting customers who don't want the calories, health effects or potential hangovers from drinking alcohol — but still want something special to drink socially.

Paul, Ronald Richard — St. Louis, MO

A coalition of cyclists wanted to call attention to traffic violence in St. Louis on Sunday — and to push for change on one of the city's deadliest thoroughfares.

The shop, at 2027 Edwards Street, was started by Stefano Gambaro, who emigrated from Genoa, Italy, to Missouri in the early 1900s.

Under the new plan the board's decision would require a supermajority of six of the board's nine members to ban a book.

Far beyond building their home into the side of a hill, the residence has a remarkable number of energy-efficient features.

Ameren also seeks to build its first large lithium-ion battery facility on the Jefferson County site of its former coal-fired Rush Island Energy Center.

Catch up on local business acquisitions, expansions and milestones.

Catch up on local business appointments, hires and promotions.

Fortified with the Sacraments of Holy Mother Church on Wed. July 9, 2025.

Margaret Agnes “Maggie” O’Connor passed away suddenly on August 11, 2024, in Manchester, Missouri.

Lilly “Marie” Lamb passed away peacefully June 27, 2025. Beloved wife of the late Thomas Lamb, Sr. Devoted mother of Janet (Daniel) Sohn, the late Thomas, Jr. (Paula Gaertner), Jeannine Lamb (Mark Schade), and Ann Lamb. Dear grandmother of Hayley…