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Emergency crews are at the scene of a crash between a small school bus and a car Tuesday morning.

May is foster Parent Appreciation Month, and Illinois state leaders are recognizing the more than 8,000 families across the state who care for foster children. However, the Department of Children and Family Services is still looking for more help.

A fundraising event to benefit three Lake St. Louis police officers injured in a police chase on I-70 in March is happening Tuesday.

Schnucks recalls ground beef sold in Granite City, Illinois.

Trying to kick the habit? SSM Health St. Clare Hospital in Fenton wants to help you stop smoking.

A man accused of shooting and killing another man, execution style in downtown St. Louis, is scheduled to appear before a judge Tuesday morning.

A blinding dust storm led to a deadly crash involving more than 70 vehicles along Interstate-55 in south central Illinois. Tuesday morning, I-55 has completely 19 hours after shutting down.

The Missouri State Auditor says he may file a lawsuit against St. Louis Circuit Attorney Kim Gardner.

Some Bonne Terre residents are expressing concerns over discolored water flowing through the water pipes inside their homes.

There's nothing like anxiously awaiting a test of the outdoor warning siren, something Thomas Wokurka of south St. Louis hasn't heard in two years.

FOX 2 has obtained an alarming new video of reckless driving in St. Louis neighborhoods.

St. Louis fashion industry leaders and rising talent celebrated while showcasing the growing industry locally at a Met Gala watch party in the Central West End.

Another homicide on the MetroLink train has left some riders shaken, but not completely deterred from riding.

DIVERNON, Ill. (AP) — A windstorm in central Illinois kicked up dangerous clouds of blinding dust off farm fields Monday, causing numerous crashes that killed at least six people on Interstate 55, police said. The late morning crashes involved 40 to 60 cars and multiple tractor-trailers, two of which caught fire, Illinois State Police Maj. [...]

HHS Secretary Becerra issues warning to hospitals that state laws do not bar providers from providing abortions to stabilize patients with complications.

Missouri voters would need approval from a majority of the state’s congressional districts or a 57% statewide vote to amend the state constitution under a proposal the Senate passed Thursday.

Two more prosecutors, in charge of the most serious cases, have now walked out of the St. Louis Circuit Attorney’s Office.

Gusty winds are causing allergy sufferers to struggle with all the pollen blowing around in the air.

A windstorm in south-central Illinois kicked up clouds of dust Monday, causing numerous crashes, pileups and “multiple fatalities” on Interstate 55, police said. The crashes occurred late in the morning and involved 40 to 60 passenger cars and multiple tractor-trailers, two of which caught fire, Illinois State Police Maj. Ryan Starrick said. The highway was [...]

The owner of a mail-order pharmacy in Creve Coeur appeared in federal court on Monday and admitted defrauding federal Medicare and state Medicaid programs of more than $5.5 million through an ongoing kickback scheme.