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The university’s Center for Vaccine Development is recruiting people for a study into pre-existing flu immunity in healthy adults.

St. Louis police are investigating a series of online death threats against the head of the City Emergency Management Agency in the wake of the May 16 tornado.

St. Louis Mayor Cara Spencer says the city is prioritizing recovery and safety as crews assess tornado-damaged properties and is not currently focused on condemning them.

Rapper Sexyy Red is offering encouragement and support for her hometown and those affected by the St. Louis tornado.

Brandon Harrill watches FOX 2 news every night. His teachers with the Bridges program in Belleville asked us if we could surprise him on his graduation day from the four-year program. 

A St. Louis County man admitted to stealing more than $153,000 in government benefits by concealing the death of a family member for over a decade.

A man was taken into custody after a police chase that began in Illinois and ended in Missouri, where he jumped or fell into the Mississippi River and was later found and taken to a nearby hospital.

WASHINGTON (AP) — House Republicans stayed up all night to pass their multitrillion-dollar tax breaks package, with Speaker Mike Johnson defying the skeptics and unifying his ranks to muscle President Donald Trump's priority bill to approval Thursday. With last-minute concessions and stark warnings from Trump, the Republican holdouts largely dropped their opposition to salvage the [...]

FOX 2, St. Louis 11, and KMOX are teaming up with the American Red Cross to help support St. Louisans devastated by last week's deadly tornado.

ST. LOUIS - Another day of breezy and cooler weather Thursday, though the winds won’t be quite as strong. We’ll start the day with sunshine but see clouds increase into Thursday afternoon. High temperatures will be in the mid- to upper 60s. The skies will clear up again during the evening. Wake up temperatures Friday [...]

Boaters at the Lake of the Ozarks are experiencing a heavy amount of debris scattered across the main channel as well as many coves up and down the massive man-made lake.

When a tornado strikes, the immediate destruction is evident, but after the skies clear, many families must deal with damage that goes beyond mere cosmetics.

Her home has been without power since Friday, when a deadly tornado tore through the city.

The head of the Missouri Gaming Commission now says legalized sports gaming will launch on Dec. 1, 2025, more than a year after voters approved Amendment 2, legalizing sports gaming in the state.

Many are still questioning whether the city could have done more to warn its residents in the moments before the storm hit.

FOX 2's Mandy Murphey had the chance to surprise a superfan.

Two pieces of paper—which the Missouri Office of Notaries and Commissions says were forged—cost an entire family their home.

A student from Seckman High School, located in Imperial, Missouri, was hit by a school bus on Wednesday.

St. Louis County has one of the largest outdoor warning siren systems in the country. National Weather Service alerts come into its emergency communications center, where the sirens can be sounded with the click of a mouse.

Why? A big question for just three letters.