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St. Louis city leaders are trying to make a change after they say they are receiving an increasing number in opioid overdose cases daily.

Police are investigating two separate shootings along Interstate 70. One happened Tuesday afternoon and the other happened overnight, just north of downtown St. Louis.

A St. Louis man reached a plea deal with city prosecutors and avoided going to trial next week for a 2021 fatal shooting in the city's Bevo neighborhood.

UPDATE: The man has returned home, according to police. JEFFERSON COUNTY, Mo. - The Jefferson County Sheriff's Office has issued an Endangered Silver Advisory for an 81-year-old man. He left his home in the 6000 block of Ozark Drive in High Ridge around 11 a.m. Wednesday. According to police, he fled his residence in a [...]

Parkway School District Superintendent Dr. Keith Marty has announced his retirement at the end of the 2024-25 school year, after 14 years in the role, during which he oversaw the passage of three bond issues and the introduction of programs like Spark! and Early College.

Nolan Arenado homered, Alec Burleson added an RBI double to back up a solid start by Miles Mikolas and the St. Louis Cardinals beat the Houston Astros 4-2 on Wednesday.

A Collinsville, Illinois, man is due in court next month to face charges that he and another man stole tens of thousands of dollars from a pair of ATM machines in Spanish Lake.

You may be tempted to use headphones while driving if your car radio isn't working or if you want to listen to a timely phone call.

The U.S. Army Corps of Engineers has successfully removed all contaminated soil from the banks of Coldwater Creek near Jana Elementary School, with 7,416 cubic yards of radioactive-contaminated soil being shipped out of state to licensed disposal facilities.

A St. Louis County man has been charged with first-degree attempted burglary and resisting arrest after attempting to enter a home in the 8800 block of Clifton Avenue, and was found with a bag of brown tar substance.

Authorities shared new video Wednesday of two suspects attempting to break into a car in St. Louis' Shaw neighborhood.

A sexually transmitted disease that is said to turn cicadas into "zombies" and causes their genitals to fall off has been detected in southern parts of Illinois and is spreading throughout the Midwest.

Tens of thousands enjoyed NASCAR festivities at World Wide Technology Raceway over the weekend in Madison, Illinois, though the events were often labeled or described as being ones for St. Louis or the St. Louis region.

Parkland Health Center-Bonne Terre has become the first rural emergency hospital in Missouri, providing expanded emergency services and transitioning patients to Parkland Health Center in Farmington for inpatient care.

A 16-year-old St. Louis juvenile was charged with first-degree murder, first-degree robbery, and two counts of armed criminal action for the 2023 shooting of Robert Green, who was found dead in the 5100 block of Greer Avenue.

The St. Louis Symphony Orchestra has announced additional shows for its 2024/2025 season, including special concerts, electronic dance music performances, and collaborations with artists such as Celtic Woman, Take 6, and Brian Stokes Mitchell.

Festus city officials recently spent $169,000 to purchase a home next to its city hall and police station, which will be knocked down to make way for a parking lot.

A St. Louis County woman started crying after winning the top prize on a "$1,000,000 Black Diamond" scratchers ticket.

The Missouri Supreme Court on Tuesday set a Sept. 24 execution date for Marcellus Williams, even as the inmate awaits a court hearing on his claim that he was not involved in the murder that landed him on death row.

CHICAGO (WMBD) -- A lucky Illinois lottery player won big Tuesday night. According to a Mega Millions news release, someone in Illinois bought the winning $552 million jackpot ticket. The winner bought the ticket while playing on the lottery's mobile app. The winning numbers were 19, 37, 40, 63 and 69 with the Mega Ball [...]