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As Geneoscopy kicked off a clinical trial for its at-home screening test for colorectal cancer, it employed a novel approach that bucks the traditional model for securing participants in the study. Its strategy is one it says offers a solution to a major, long-standing problem: an underrepresentation of minorities in the clinical trials. The St. Louis startup says it’s already seeing promising results.

A federal report, from the third quarter of 2021, shows Lambert is in the top quarter nationally for cheap airfares.

Archbishop of St. Louis Mitchell Rozanski said it’s time to make some big changes within the archdiocese. He is launching a strategic plan initiative that could reshape parishes, schools, charities and priest personnel. The plan is called “All Things New” and Rozanski wants Catholics across the region to weigh in on what changes may be necessary. “What structures are needed, what structures are not needed? How do we need to be adapting as a church to our current times, to the demographic…

Missouri Gov. Mike Parson said Friday he's nominating three people for the board that owns the Dome at America's Center and is set to receive Rams settlement money.

Hispanic Chamber of Commerce of Metropolitan St. Louis has hired Edùardo Platon as its new president and chief executive officer.

“These innovative programs not only include work-and-learn opportunities and mentorship, but also targeted recruitment of women, people of color, rural residents and others from underserved communities to ensure that STEM fields are diverse, equitable and inclusive,” Alejandra Castillo, assistant secretary of commerce for economic development, said in a written statement.

In the last three years, the downtown St. Louis craft brewery has also added a distillery to its portfolio, branched into hard seltzers and canned cocktails, launched a whiskey label and this year will expand into nonalcoholic beverages. Its CEO explains why broadening its portfolio doesn't weaken what it does best.

The 63-year-old design-build construction company's new CEO has nearly 28 years of construction experience.

I was thinking about the “long” time lag between Nov. 15 and Jan. 20, when “the mail” showed up. Really, nothing was lost and one could easily imagine back, way back, regarding the travel of the written word or any information.

The Rockwood Board of Education has named Curtis Cain as the district’s next superintendent. Cain will begin his new role on July 1. He replaces Timothy Ricker, who has been serving as the interim superintendent since July 2021 after Mark Miles retired. Cain currently serves as the superintendent of the Wentzville School District where he has worked since 2013, according to a news release from Rockwood. He will stay in his current role at Wentzville through the end of the school year. Prior to…

The new member marks the third university since September to sign on to join the Missouri Valley Conference, which is one of several Division 1 athletic conferences nationwide that has recently experienced changes to its membership. The addition also maintains the league's presence in Chicago.

Closings and pending sales of single-family homes were down last month compared with December 2020, but median sales prices rose over the period, according to trade group St. Louis Realtors.

Stifel said recent studies have found that businesses run by women have strong performance, but receive less capital from the institutional venture and private equity communities.

Real estate investors are rehabbing and selling homes north of Delmar Boulevard, transactions that are bringing unheard-of prices for the area and leading to hope that the region’s long-standing dividing line for race and wealth may be starting to break down.

The St. Louis Business Journal has extended the nomination deadline for its 2022 Innovation in Philanthropy Awards, which seek to highlight the contributions St. Louis businesses have made to their communities through innovative partnerships. Nominations are now being accepted until Friday, Feb. 4. You can submit your nomination at the link here. These awards highlight companies and organizations that are going above and beyond the standard philanthropic practices to evolve programs in our communities.…

The Illinois Legislature will consider possible statewide standards for warehouse construction, following the collapse of an Amazon warehouse in Edwardsville during a tornado in December.

Dierbergs Markets and McBride Homes closed Wednesday on the purchase of the former Crestwood Plaza mall site in south St. Louis County.

“St. Louis has created an immense amount of opportunity to make a living, grow a business and play with all kinds of side projects and ideas, and do it in a place that has a modest cost of living, great old buildings and people who are willing to help and want to see each other succeed,” said Chris Ryan, owner and director of Once Films.

The official is no longer executive director of Metro Transit, and the organization is searching for her successor.

St. Charles County reported strong building activity last year, led by growth in the residential sector. It counted 1,723 single-family building permits in 2021, off from 1,778 in 2020 but still elevated from pre-pandemic figures. Multifamily permits set a record, at 1,202, up from 1,173 in 2020, the county government said. Together, the residential permits were worth $658 million in 2021, flat from 2020 but up from $556 million in 2019. The county's director of community development, Mike…