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Estimated opioid overdose deaths in the United States surpassed 100,000 for the first time for the 12-month period ending in April 2021.

Justin King, 28, was killed by a neighbor in Bourbon, Missouri. The county prosecutor says the shooting was self-defense under Missouri law, but civil rights activists say that’s not the full story.

Narcan can effectively treat a narcotics overdose.

Fewer than one in five vaccine-eligible children in St. Louis have gotten their full inoculation, but that rate still ranks near the top statewide, as new data show Missouri continues to struggle in protecting children from COVID-19.

Missouri is among many states where vaccination rates for young children between the ages of five and eleven have stalled.…

"With this verdict, the families of Shari, AJ, and John can know both of these killers will spend the rest of their lives in jail."

Here’s a sampling of the many shows headed to St. Louis-area venues in 2022.

St. Louis Public Radio statehouse reporter Sarah Kellogg discusses what the Missouri legislature has been working on in its first two weeks this year, and what’s to come this session.

The deal involves a firm with more than 500 real estate agents and $1.3 billion in 2021 sales volume.

The Supreme Court's ruling Thursday related only to the federal agency's vaccine mandate-or-testing rule, and it doesn't prohibit companies enacting mandates of their own. A pair of St. Louis lawyers explain why that makes for a challenging landscape for companies operating in multiple states.

Rolling Stone has unveiled its list of the 10 highest-earning music artists for 2021, and the tally is made up mostly up veteran acts who sold the rights to their…

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A government transparency advocate argued Friday that the Missouri House of Representatives is defying the will of the voters by withholding information from the public when responding to open records requests. Whether the Missouri House has the authority to withhold information, including the addresses and phone numbers of constituents, was at the heart of a […]

The post Missouri judge hears arguments over whether legislative rule violates open records law appeared first on Missouri Independent.

Another one bites the dust – at least, temporarily. Fuzzy’s Taco Shop announced in an email to customers Thursday it is closing its four St. Louis-area locations and Columbia, Missouri, restaurant “for the time being.” “We love our Fuzzy’s fans and the good vibes you bring us. We look forward to seeing your faces again soon,” the email stated. “It’s not a goodbye, it’s a see you later.” Fuzzy’s did not give a reason for the temporary closure. The restaurant chain's St.…

NORMANDY, Mo. (AP) — School districts struggling with staff absences because of COVID-19 are facing difficult decisions about how to provide the required number of instruction hours while being limited …

Jalon Moore robbed two business and a bank in Illinois and robbed or tried to rob five businesses in Missouri in 2019.

5 On Your Side investigative journalist PJ Randhawa's work led to changes in St. Louis. She now heads to KING 5 in Seattle.

A development executive returns to the St. Louis Symphony Orchestra as its new vice president and chief philanthropy officer after holding several roles at another local nonprofit.